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Home Antibody All anti-HSPH1 antibodies

Anti-HSPH1 Antibody N/A

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA326392
  • Rabbit polyclonal Hsp110 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC402001) , 20ug Explanation
100µg 325 3-7 Days
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WB(1)
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Also for HSPH1 (NM_006644)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenSynthetic peptide derived from the sequence of hamster Hsp110; sequence identical to human and mouse
Clone NameN/A IsotypeN/A
Species ReactivityHuman, Monkey, Hamster, Rat, Mouse, Cow, Sheep, Yeast Concentration1mg/mL
Guaranteed Application *WB Suggested DilutionsWB: 1:1000
BufferPBS pH7.2, 50% glycerol, 0.09% sodium azide
Purification Affinity Purified
Note Detects ~110kDa

Reference Data

Target NameHomo sapiens heat shock 105kDa/110kDa protein 1 (HSPH1), transcript variant 1
Alternative NameHSP105; HSP105A; HSP105B; NY-CO-25
Database LinkNP_006635
Entrez Gene 10808 Human
Entrez Gene 15505 Mouse
Entrez Gene 288444 Rat
Entrez Gene 721956 Monkey
FunctionHsp110 belongs to a family of large stress proteins known as the Hsp110/SSE Family. The proteins in this family are the most distantly known relatives of the well studied Hsp70 family. They share 30-33% amino acid identity, mostly in the conserved ATP-binding domain . Hsp110 cooperates with Hsp70 in protein folding in the eukaryotic cytosol . In mammals, Hsp110 is constitutively expressed, but exhibits particularly high levels in the brain. Both Hsp70 and Hsp110 are elevated after cerebral ischemia. Recent studies demonstrate that the protective effects of Hsp110 deficiency in cerebral ischemia may partly be mediated by an increase in the chaperone activity of Hsp70 . Studies also suggest that Hsp110 can be used in heat shock protein-based cancer immunotherapy .
Related PathwayStem cell - Pluripotency

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of Hsp110 in a human cell mix using a 1:1000 dilution of the antibody

 

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