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Anti-STAT1 PHOSPHO Antibody
Also for STAT1 (NM_007315)
|The antiserum was produced against a synthesized A synthesized peptide derived from human STAT1 around the phosphorylation site of Sersine 727.|
|Human, Mouse, Rat
||WB: 1:500-1:2000; IHC: 1:50-1:200
|Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
|Homo sapiens signal transducer and activator of transcription 1, 91kDa (STAT1), transcript variant alpha|
|CANDF7; ISGF-3; STAT91|
|The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.|
EGFR1 Signaling Pathway
Jak-STAT signaling pathway
TGF Beta Signaling Pathway
Toll-like receptor signaling pathway
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Western blot analysis on Jurkat cell lysate using Phospho-STAT1(Ser727) Antibody
Immunohistochemical analysis of paraffin-embedded breast carcinoma tissue using Phospho- STAT1 (Ser727) Antibody.