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Anti-SHC1 PHOSPHO Antibody
Also for SHC1 (NM_001130040)
|The antiserum was produced against A synthesized peptide derived from human Shc around the phosphorylation site of Tyrosine 349|
|Human, Mouse, Rat
||WB: 1:500-1:2000; IHC: 1:50-1:200
|Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
|Homo sapiens SHC (Src homology 2 domain containing) transforming protein 1 (SHC1), transcript variant 3|
|Shc1 IS an adaptor protein containing a SH2 domain and a PID domain within a PH domain-like fold. Three isoforms(p66, p52 and p46), produced by alternative initiation, variously regulate growth factor signaling, oncogenesis and apoptosis.|
EGFR1 Signaling Pathway
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Western blot analysis of Shc phosphorylation expression in EGF treated 293 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.