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Anti-RAF1 PHOSPHO Antibody
Also for RAF1 (NM_002880)
|The antiserum was produced against A synthesized peptide derived from human C-RAF around the phosphorylation site of Serine 621|
|Human, Mouse, Rat
||WB: 1:500-1:2000; IHC: 1:50-1:200; IF/ICC: 1:100-1:500
|Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
|Homo sapiens Raf-1 proto-oncogene, serine/threonine kinase (RAF1)|
|c-Raf; CMD1NN; CRAF; NS5; Raf-1|
|Raf-1 is a MAP kinase kinase kinase (MAP3K) which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated Raf-1 can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2 which in turn|
EGFR1 Signaling Pathway
MAPK signaling pathway
Senescence and Autophagy
Wnt Signaling Pathway
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Western blot analysis of C-RAF phosphorylation expression in UV treated HeLa whole cell lysates,The lane on the left is treated with the antigen-specific peptide.