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TA325771 Rabbit Polyclonal PDGFR beta (Tyr740) Antibody (Phospho-specific) 100ul 325
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Also for PDGFRB (NM_002609)
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OriGene Data

ImmunogenThe antiserum was produced against A synthesized peptide derived from human PDGFR beta around the phosphorylation site of Tyrosine 740
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1:500-1:2000; IHC: 1:50-1:200
Predicted MW Explanation 170kDa
BufferRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.

Reference Data

Target NameHomo sapiens platelet-derived growth factor receptor, beta polypeptide (PDGFRB)
Alternative NameCD140B; IBGC4; IMF1; JTK12; PDGFR; PDGFR-1; PDGFR1
Database LinkNP_002600
Entrez Gene 5159 Human
Entrez Gene 18596 Mouse
Entrez Gene 24629 Rat
FunctionThis gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides.
Related PathwayProtein KinaseES Cell Differentiation/IPSTransmembraneDruggable Genome MAPK signaling pathwayCalcium signaling pathwayCytokine-cytokine receptor interactionFocal adhesionGap junctionRegulation of actin cytoskeletonMore Pathways >>

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WB Image
Western blot analysis of PDGFR beta phosphorylation expression in EGF treated HepG2 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.


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