Home Antibody All anti-JUP antibodies
|The antiserum was produced against a synthesized A synthesized peptide derived from human Catenin-gamma.|
|Human, Mouse, Rat
||WB: 1:500-1:2000; IHC: 1:50-1:200
|Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
|Homo sapiens junction plakoglobin (JUP), transcript variant 1|
|ARVD12; CTNNG; DP3; DPIII; PDGB; PKGB|
|desmoplakin 3 Common junctional plaque protein. The membrane- associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE- cadherin function in endothelial cells. Belongs to the beta-catenin family. Homodimer. Interacts with MUC1.|
Wnt Signaling Pathway
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Western blot analysis on HeLa cell lysate using Catenin-gamma Antibody
Immunohistochemical analysis of paraffin-embedded breast carcinoma tissue using Catenin-? Antibody.