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Anti-H2AFX PHOSPHO Antibody
Also for H2AFX (NM_002105)
|The antiserum was produced against A synthesized peptide derived from human Histone H2A.X around the phosphorylation site of Serine 139|
|Human, Mouse, Rat
|Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
|Homo sapiens H2A histone family, member X (H2AFX)|
|H2A.X; H2A/X; H2AX|
|Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes.|
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Western blot analysis of Histone H2A.X phosphorylation expression in UV treated HeLa whole cell lysates,The lane on the left is treated with the antigen-specific peptide.