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Home Antibody All anti-FOSB antibodies

Anti-FOSB PHOSPHO Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA325470
  • Rabbit Polyclonal FosB (Ser27) Antibody (Phospho-specific)
100ul 325 3 Weeks
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WB(1)
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Also for FOSB (NM_001114171)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenA synthesized peptide derived from human FosB around the phosphorylation site of Sersine 27
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1:500-1:2000
BufferRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.

Reference Data

Target NameHomo sapiens FBJ murine osteosarcoma viral oncogene homolog B (FOSB), transcript variant 2
Alternative NameAP-1; G0S3; GOS3; GOSB
Database LinkNP_001107643
Entrez Gene 2354 Human
Entrez Gene 14282 Mouse
FunctionFos and Jun dimerize to form Activator Protein-1 (AP-1), a transcriptional factor that binds to the 12-O-tetradecanoylphorbol 13-acetate (TPA) response element (TRE) of several cellular and viral genes including human collagenase, metallothionein IIa, stromelysin, interleukin 2, SV40 and polyoma. Fos and Jun contain the ‘leucine-zipper’ motif that allows for dimerization and an adjacent basic domain required for biological activity. The functionally active form of Fos is in a heterodimer with a member of the Jun family. While Jun family members can form functional homodimers, studies indicate that Fos family members do not self-associate and therefore do not bind DNA on their own. The various dimers differ in their ability to transactivate AP-1 dependent genes.
Related PathwayTranscription FactorsDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis on A549 cell lysate using Phospho-FosB (Ser27) Antibody.The lane on the right is treated with the synthesized peptide.

 

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