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Home Antibody All anti-CHEK2 antibodies

Anti-CHEK2 PHOSPHO Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA325376 Rabbit Polyclonal Chk2 (Thr387) Antibody (Phospho-specific) 100ul 325
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OriGene Data

ImmunogenThe antiserum was produced against A synthesized peptide derived from human Chk2 around the phosphorylation site of Threonine 387
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1:500-1:2000; IHC: 1:50-1:200
Predicted MW Explanation 62kDa
BufferRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.

Reference Data

Target NameHomo sapiens checkpoint kinase 2 (CHEK2), transcript variant 3
Alternative NameCDS1; CHK2; hCds1; HuCds1; LFS2; PP1425; RAD53
Database LinkNP_001005735
Entrez Gene 11200 Human
Entrez Gene 50883 Mouse
Entrez Gene 114212 Rat
FunctionIn response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators. The protein encoded by this gene is a cell cycle checkpoint regulator and putative tumor suppressor.
Related PathwayProtein KinaseStem cell - PluripotencyDruggable Genome Cell cyclep53 signaling pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of Chk2 phosphorylation expression in Jurkat whole cell lysates,The lane on the left is treated with the antigen-specific peptide.


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