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Anti-CCR5 PHOSPHO Antibody


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SKU Description Amount Price Availability*  
TA325319 Rabbit Polyclonal CCR5 (Ser336) Antibody (Phospho-specific) 100ul 325
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OriGene Data

ImmunogenThe antiserum was produced against A synthesized peptide derived from human CCR5 around the phosphorylation site of Serine 336
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1:500-1:2000
Predicted MW Explanation 40kDa
BufferRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.

Reference Data

Target NameHomo sapiens chemokine (C-C motif) receptor 5 (gene/pseudogene) (CCR5), transcript variant A
Alternative NameCC-CKR-5; CCCKR5; CCR-5; CD195; CKR-5; CKR5; CMKBR5; IDDM22
Database LinkNP_000570
Entrez Gene 1234 Human
Entrez Gene 12774 Mouse
Entrez Gene 117029 Rat
FunctionCCR5 a 7-transmembrane G-linked receptor for a number of inflammatory C-C type chemokines including MIP-1-alpha, MIP-1-beta and RANTES. Transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (along with CD4) for HIV-1 R5 isolates. Interacts with PRAF2. Interacts with HIV-1 surface protein gp120.
Related PathwayGPCRES Cell Differentiation/IPSTransmembraneDruggable Genome Cytokine-cytokine receptor interactionChemokine signaling pathwayEndocytosis

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Western blot analysis of CCR5 phosphorylation expression in Jurkat whole cell lysates,The lane on the left is treated with the antigen-specific peptide.


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