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Home Antibody All anti-CASP8 antibodies

Anti-CASP8 PHOSPHO Antibody


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SKU Description Amount Price Availability*  
TA325296 Rabbit Polyclonal Caspase 8 (Ser347) Antibody (Phospho-specific) 100ul 325
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Also for CASP8 (NM_001080124)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Request Assay

OriGene Data

ImmunogenThe antiserum was produced against A synthesized peptide derived from human Caspase 8 around the phosphorylation site of Serine 347
Clone Name IsotypeIgG
Species ReactivityHuman, Rat Concentration1 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1:500-1:2000; IHC: 1:50-1:200
Predicted MW Explanation 57kDa
BufferRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.

Reference Data

Target NameHomo sapiens caspase 8, apoptosis-related cysteine peptidase (CASP8), transcript variant F
Alternative NameALPS2B; CAP4; Casp-8; FLICE; MACH; MCH5
Database LinkNP_001073593
Entrez Gene 841 Human
Entrez Gene 64044 Rat
FunctionThis gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits.
Related PathwayProteaseDruggable Genome p53 signaling pathwayApoptosisToll-like receptor signaling pathwayNOD-like receptor signaling pathwayRIG-I-like receptor signaling pathwayAlzheimer's diseaseMore Pathways >>

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of Caspase 8 phosphorylation expression in Jurkat whole cell lysates,The lane on the left is treated with the antigen-specific peptide.


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