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Home Antibody All anti-WNT5A antibodies

Anti-WNT5A Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA324222 Anti-WNT5A Rabbit Polyclonal Antibody 100ul $325 2-3 Weeks
LC401155 WNT5A HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenFusion protein corresponding to C terminal 280 amino acids of human wingless-type MMTV integration site family, member 5A
Clone Name IsotypeIgG
Species ReactivityHuman; Mouse; Rat Concentration0.62mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1:500-2000
Predicted MW Explanation 42kDa
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameWnt family member 5A
Alternative NamehWNT5A
Database LinkNP_001243034
Entrez Gene 7474 Human
Entrez Gene 22418 Mouse
Entrez Gene 64566 Rat
FunctionThe Wnt family includes several secreted glycoproteins that play important roles in animal development. There are 19 Wnt genes in the human genome that encode functionally distinct Wnt proteins. Wnt members bind to the Frizzled family of seven-pass transmembrane proteins and activate several signaling pathways. The canonical Wnt/ß-catenin pathway also requires a coreceptor from the low-density lipoprotein receptor family. Aberrant activation of Wnt signaling pathways is involved in several types of cancers. Wnt-5a has been shown to signal through the canonical Wnt pathways as well as through non-canonical pathways and is up-regulated in various types of human cancers. In melanoma, Wnt5a is thought to directly affect cell motility and metastasis.
Related PathwayStem cell relevant signaling - Wnt Signaling pathwaySecreted ProteinES Cell Differentiation/IPSAdult stem cellsCancer stem cellsDruggable Genome Wnt signaling pathwayHedgehog signaling pathwayMelanogenesisPathways in cancerBasal cell carcinoma

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Predicted band size: 42 kDa . Positive control: Mouse heart tissue lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lysate: 40 ug Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)


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