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Home Antibody All anti-WNT5A antibodies

Anti-WNT5A Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA324222
  • Anti-WNT5A Rabbit Polyclonal Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC401155) , 20ug
100ul $325 2-3 Weeks
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WB(1)

OriGene Data

ImmunogenFusion protein corresponding to C terminal 280 amino acids of human wingless-type MMTV integration site family, member 5A
Clone Name IsotypeIgG
Species ReactivityHuman; Mouse; Rat Concentration0.62mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1:500-2000
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens wingless-type MMTV integration site family, member 5A (WNT5A), transcript variant 2
Alternative NamehWNT5A
Database LinkNP_001243034
FunctionThe Wnt family includes several secreted glycoproteins that play important roles in animal development. There are 19 Wnt genes in the human genome that encode functionally distinct Wnt proteins. Wnt members bind to the Frizzled family of seven-pass transmembrane proteins and activate several signaling pathways. The canonical Wnt/ß-catenin pathway also requires a coreceptor from the low-density lipoprotein receptor family. Aberrant activation of Wnt signaling pathways is involved in several types of cancers. Wnt-5a has been shown to signal through the canonical Wnt pathways as well as through non-canonical pathways and is up-regulated in various types of human cancers. In melanoma, Wnt5a is thought to directly affect cell motility and metastasis.
Related Pathway
Hedgehog signaling pathway
Melanogenesis
Wnt Signaling Pathway

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WB Image
Predicted band size: 42 kDa . Positive control: Mouse heart tissue lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lysate: 40 ug Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)

 

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