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Home Antibody All anti-BACE1 antibodies

Anti-BACE1 Antibody

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SKU Description Amount Price Availability*  
TA324168 Anti-BACE1 Rabbit Polyclonal Antibody 100ul $325 2-3 Weeks
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IHC(2)

OriGene Data

ImmunogenFusion protein corresponding to C terminal 300 amino acids of human beta-site APP-cleaving enzyme 1
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5mg/ml
Guaranteed Application *IHC Suggested DilutionsELISA: 1:1000-2000, IHC: 1:15-50
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens beta-site APP-cleaving enzyme 1 (BACE1), transcript variant d
Alternative NameASP2; BACE; HSPC104
Database LinkNP_620429
Entrez Gene 23621 Human
Entrez Gene 23821 Mouse
Entrez Gene 29392 Rat
FunctionCerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene.?
Related PathwayTransmembraneProteaseDruggable Genome Alzheimer's disease

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Predicted cell location: Cytoplasm. Positive control: Human thyroid and liver cancer tissue. Recommended dilution: 1/15-50 The image on the left is immunohistochemistry of paraffin-embedded human thyroid cancer tissue using BACE1 antibody at dilution 1/15, on the right is treated with the fusion protein. (Original magnification:x 200)
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Predicted cell location: Cytoplasm. Positive control: Human thyroid and liver cancer tissue. Recommended dilution: 1/15-50 The image on the left is immunohistochemistry of paraffin-embedded human liver cancer tissue using BACE1 antibody at dilution 1/15, on the right is treated with the fusion protein. (Original magnification:x200)
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