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Home Antibody All anti-OCLN antibodies

Anti-OCLN Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA324149
  • Anti-OCLN Rabbit Polyclonal Antibody
100ul 325 2-3 Weeks
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IHC(2)
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Also for OCLN (NM_002538)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFusion protein corresponding to a region derived from 266-522 amino acids of human occludin
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.3mg/ml
Guaranteed Application *IHC Suggested DilutionsELISA: 1:1000-2000, IHC: 1:15-50
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens occludin (OCLN), transcript variant 1
Alternative NameBLCPMG; PPP1R115
Database LinkNP_002529
Entrez Gene 100506658 Human
Entrez Gene 18260 Mouse
Entrez Gene 83497 Rat
FunctionThis gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG); an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

IHC Image
Predicted cell location: Cytoplasm . Positive control: Human colon and lung cancer tissue. Recommended dilution: 1/15-50 The image on the left is immunohistochemistry of paraffin-embedded human colon cancer tissue using OCLN antibody at dilution 1/10, on the right is treated with the fusion protein. (Original magnification:x 200)
IHC Image
Predicted cell location: Cytoplasm . Positive control: Human colon and lung cancer tissue. Recommended dilution: 1/15-50 The image on the left is immunohistochemistry of paraffin-embedded human lung cancer tissue using OCLN antibody at dilution 1/10, on the right is treated with the fusion protein. (Original magnification:x200)

 

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