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Home Antibody All anti-MYH7 antibodies

Anti-MYH7 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA323707
  • Anti-MYH7 Rabbit Polyclonal Antibody
100ul 325 2-3 Weeks
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IHC(2)

OriGene Data

ImmunogenFusion protein corresponding to C terminal 300 amino acids of human myosin, heavy chain 7, cardiac muscle, beta
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.7mg/ml
Guaranteed Application *IHC Suggested DilutionsELISA: 1:1000-5000, IHC: 1:25-100
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens myosin, heavy chain 7, cardiac muscle, beta (MYH7)
Alternative NameCMD1S; CMH1; MPD1; MYHCB; SPMD; SPMM
Database LinkNP_000248
Entrez Gene 4625 Human
Entrez Gene 140781 Mouse
Entrez Gene 29557 Rat
FunctionMuscle myosin is a hexameric protein containing 2 heavy chain subunits; 2 alkali light chain subunits; and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy; myosin storage myopathy; dilated cardiomyopathy; and Laing early-onset distal myopathy.
Related Pathway Cardiac muscle contractionTight junctionHypertrophic cardiomyopathy (HCM)Dilated cardiomyopathyViral myocarditis

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

IHC Image
Predicted cell location: Cytoplasm . Positive control: Human tonsil and thyroid cancer tissue. Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded human tonsil tissue using MYH7 antibody at dilution 1/20, on the right is treated with the fusion protein. (Original magnification:x 200)
IHC Image
Predicted cell location: Cytoplasm . Positive control: Human tonsil and thyroid cancer tissue. Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded human thyroid cancer tissue using MYH7 antibody at dilution 1/20, on the right is treated with the fusion protein. (Original magnification:x200)

 

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