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Home Antibody All anti-BIRC5 antibodies

Anti-BIRC5 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA323463
  • Anti-BIRC5 Rabbit Polyclonal Antibody
100ul 325 2-3 Weeks
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IHC(1)
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Also for BIRC5 (NM_001168)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length fusion protein
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5mg/ml
Guaranteed Application *IHC Suggested DilutionsELISA: 1:1000-5000, IHC: 1:10-50
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens baculoviral IAP repeat containing 5 (BIRC5), transcript variant 1
Alternative NameAPI4; EPR-1
Database LinkNP_001159
Entrez Gene 332 Human
Entrez Gene 11799 Mouse
Entrez Gene 64041 Rat
FunctionThis gene is a member of the inhibitor of apoptosis (IAP) gene family; which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains; but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors; yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Related PathwayStem cell - PluripotencyDruggable Genome Pathways in cancerColorectal cancer

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

IHC Image
Predicted cell location: Cytoplasm . Positive control: Human lung cancer tissue. Recommended dilution: 1 /10-50 The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using BIRC5 antibody at dilution 1/25, on the right is treated with the fusion protein. (Original magnification: x100)

 

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