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Home Antibody All anti-ZYX antibodies

Anti-ZYX Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA323459
  • Anti-ZYX Rabbit Polyclonal Antibody
100ul 325 2-3 Weeks
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WB(1)
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Also for ZYX (NM_001010972)
cDNA Clone shRNA/siRNA Primer Pair Protein Antibody

OriGene Data

ImmunogenFusion protein corresponding to N terminal 300 amino acids of human zyxin
Clone Name IsotypeIgG
Species ReactivityHuman; Mouse; Rat Concentration5.11mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1:500-2000
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens zyxin (ZYX), transcript variant 2
Alternative NameESP-2; HED-2
Database LinkNP_001010972
FunctionThe zyxin family of proteins includes LIMD1, ajuba, trip6 and zyxin, each of which contains three LIM domains at the carboxy-terminus. Zyxin family members associate with the actin cytoskeleton and are components of both the cell-cell junction adhesive complex and the integrin-mediated adhesive complex. They shuttle in and out of the nucleus where they may function in transcriptional activation.Zyxin is involved in the regulation of mechanical force-induced actin polymerization at focal adhesions, and in regulation of adhesion and migration, possibly through recruitment of Ena/VASP proteins to focal adhesions. Zyxin interacts with and may regulate the function of the tumor suppressor myopodin, which inhibits tumor growth and metastasis.
Related Pathway
Focal Adhesion

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Predicted band size: 80 kDa . Positive control: HeLa cell lysate. Recommended dilution: 1/500-2000. (Gel: 8%SDS-PAGE Lysate: 40 ug Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)

 

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