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Home Antibody All anti-ZYX antibodies

Anti-ZYX Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA323459
  • Anti-ZYX Rabbit Polyclonal Antibody
100ul 325 2-3 Weeks
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WB(1)
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Also for ZYX (NM_001010972)
cDNA Clone shRNA/siRNA Primer Pair Protein Antibody

OriGene Data

ImmunogenFusion protein corresponding to N terminal 300 amino acids of human zyxin
Clone Name IsotypeIgG
Species ReactivityHuman; Mouse; Rat Concentration5.11mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1:500-2000
Predicted MW Explanation 80kDa
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens zyxin (ZYX), transcript variant 2
Alternative NameESP-2; HED-2
Database LinkNP_001010972
Entrez Gene 7791 Human
Entrez Gene 22793 Mouse
Entrez Gene 114636 Rat
FunctionThe zyxin family of proteins includes LIMD1, ajuba, trip6 and zyxin, each of which contains three LIM domains at the carboxy-terminus. Zyxin family members associate with the actin cytoskeleton and are components of both the cell-cell junction adhesive complex and the integrin-mediated adhesive complex. They shuttle in and out of the nucleus where they may function in transcriptional activation.Zyxin is involved in the regulation of mechanical force-induced actin polymerization at focal adhesions, and in regulation of adhesion and migration, possibly through recruitment of Ena/VASP proteins to focal adhesions. Zyxin interacts with and may regulate the function of the tumor suppressor myopodin, which inhibits tumor growth and metastasis.
Related Pathway Focal adhesion

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Predicted band size: 80 kDa . Positive control: HeLa cell lysate. Recommended dilution: 1/500-2000. (Gel: 8%SDS-PAGE Lysate: 40 ug Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)

 

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