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Home Antibody All anti-BMP4 antibodies

Anti-BMP4 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA323209 Anti-BMP4 Rabbit Polyclonal Antibody 100ul 325
2-3 Weeks
LC420075 BMP4 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenFusion protein corresponding to a region derived from 293-408 amino acids of human bone morphogenetic protein 4
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.9mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsELISA: 1:1000-5000, WB: 1:200-1000, IHC: 1:25-100
Predicted MW Explanation 47kDa
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens bone morphogenetic protein 4 (BMP4), transcript variant 1
Alternative NameBMP2B; BMP2B1; MCOPS6; OFC11; ZYME
Database LinkNP_001193
Entrez Gene 652 Human
Entrez Gene 12159 Mouse
Entrez Gene 25296 Rat
FunctionThe protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans; and a reduction in expression has been associated with a variety of bone diseases; including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described; all encoding an identical protein.
Related PathwayStem cell relevant signaling - TGFb/BMP signaling pathwaySecreted ProteinAdult stem cellsCancer stem cellsEmbryonic stem cellsInduced pluripotent stem cellsDruggable Genome Hedgehog signaling pathwayTGF-beta signaling pathwayPathways in cancerBasal cell carcinoma

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Predicted band size: 47 kDa . Positive control: Mouse intestinumm tenue tissue lysate. Recommended dilution: 1/200-1000. (Gel: 10%+12%SDS-PAGE Lysate: 50 ug Primary antibody: 1/450 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 20 minutes)

IHC Image
Predicted cell location: Cytoplasm. Positive control: Human brain tissue. Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using BMP4 antibody at dilution 1/25, on the right is treated with the fusion protein. (Original magnification: x200)


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