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Home Antibody All anti-EDNRB antibodies

Anti-EDNRB Antibody

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SKU Description Amount Price Availability*  
TA322809
  • Anti-EDNRB Rabbit Polyclonal Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC418304) , 20ug
100ul 325 In Stock
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WB(1)
IHC(1)

OriGene Data

ImmunogenSynthetic peptide peptide corresponding to a region derived from 70-84 amino acids of human endothelin receptor type B
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsELISA: 1:2000-5000, WB: 1:500-2000, IHC: 1:25-100
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens endothelin receptor type B (EDNRB), transcript variant 2
Alternative NameABCDS; ET-B; ET-BR; ETB; ETBR; ETRB; HSCR; HSCR2; WS4A
Database LinkNP_003982
FunctionThe protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand; endothelin; consists of a family of three potent vasoactive peptides: ET1; ET2; and ET3. Studies suggest that the multigenic disorder; Hirschsprung disease type 2; is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Related Pathway
Melanogenesis
Signaling by GPCR

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WB Image
Predicted band size: 50 kDa.Positive control: Hela cell, human lung, fetal intestine and fetal lung tissue lysate. Recommended dilution: 1/500-2000
IHC Image
Predicted cell location: Cytoplasm. Positive control: Human cervical cancer tissue. Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using EDNRB antibody at dilution 1/30, on the right is treated with the synthetic peptide. (Original magnification: x200)

 

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