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Home Antibody All anti-EGFR antibodies

Anti-EGFR Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA322654
  • Anti-EGFR Rabbit Polyclonal Antibody
100ul 325 2-3 Weeks
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IHC(2)
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Also for EGFR (NM_005228)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenSynthetic peptide corresponding to a region derived from 1003-1016 amino acids of Human epidermal growth factor receptor
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.7mg/ml
Guaranteed Application *IHC Suggested DilutionsELISA: 1:1000-2000, IHC: 1:15-50
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens epidermal growth factor receptor (EGFR), transcript variant 1
Alternative NameERBB; ERBB1; HER1; mENA; PIG61
Database LinkNP_005219
FunctionThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.
Related Pathway
Adherens junction
Cytokine-cytokine receptor interaction
Delta-Notch Signaling Pathway
EGFR1 Signaling Pathway
Focal Adhesion
MAPK signaling pathway

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IHC Image
Predicted cell location: Cytoplasm, Nucleus. Positive control: Human thyroid and colon cancer tissue. Recommended dilution: 1/15-50 The image on the left is immunohistochemistry of paraffin-embedded Human thyroid and colon cancer tissue using EGFR antibody at dilution 1/15, on the right is treated with the synthetic peptide. (Original magnification:x200)
IHC Image
Predicted cell location: Cytoplasm, Nucleus. Positive control: Human thyroid and colon cancer tissue. Recommended dilution: 1/15-50 The image on the left is immunohistochemistry of paraffin-embedded Human thyroid and colon cancer tissue using EGFR antibody at dilution 1/15, on the right is treated with the synthetic peptide. (Original magnification:x200)

 

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