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Home Antibody All anti-SRC antibodies

Anti-SRC Antibody

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Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA322606 Anti-SRC Rabbit Polyclonal Antibody 100ul $325 In Stock
LC417311 SRC HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IHC(1)

OriGene Data

ImmunogenFusion protein corresponding to a region derived from 270-523 amino acids of human v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsELISA: 1:1000-2000, WB: 1:200-1000,IHC: 1:15-50
Predicted MW Explanation 60kDa
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens SRC proto-oncogene, non-receptor tyrosine kinase (SRC), transcript variant 1
Alternative NameASV; c-SRC; p60-Src; SRC1; THC6
Database LinkNP_005408
Entrez Gene 6714 Human
Entrez Gene 20779 Mouse
Entrez Gene 83805 Rat
FunctionThis gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.?
Related PathwayStem cell relevant signaling - JAK/STAT signaling pathwayProtein KinaseES Cell Differentiation/IPSDruggable Genome ErbB signaling pathwayEndocytosisVEGF signaling pathwayFocal adhesionAdherens junctionTight junctionMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.


WB Image
Predicted band size: 60 kDa . Positive control: PC3 cell lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/100 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)
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IHC Image
Predicted cell location: Cytoplasm. Positive control: Human liver cancer tissue. Recommended dilution: 1/15-50 The image on the left is immunohistochemistry of paraffin-embedded human liver cancer tissue using SRC antibody at dilution 1/10, on the right is treated with the fusion protein. (Original magnification:x200)
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