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Home Antibody All anti-CLDN14 antibodies

Anti-CLDN14 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA322417
  • Anti-CLDN14 Rabbit Polyclonal Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC415957) , 20ug Explanation
100ul 325 2-3 Weeks
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Also for CLDN14 (NM_012130)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenSynthetic peptide corresponding to a region derived from 227-239 amino acids of Human claudin 14
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.4mg/ml
Guaranteed Application * Suggested DilutionsELISA: 1:1000-10000, WB: 1:200-1000
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens claudin 14 (CLDN14), transcript variant epsilon
Alternative NameDFNB29
Database LinkNP_036262
Entrez Gene 23562 Human
Entrez Gene 56173 Mouse
Entrez Gene 304073 Rat
FunctionTight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets; forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet; with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene; a member of the claudin family; is an integral membrane protein and a component of tight junction strands. The encoded protein also binds specifically to the WW domain of Yes-associated protein. Defects in this gene are the cause of an autosomal recessive form of nonsyndromic sensorineural deafness. It is also reported that four synonymous variants in this gene are associated with kidney stones and reduced bone mineral density. Several transcript variants encoding the same protein have been found for this gene.
Related PathwayTransmembraneDruggable Genome Cell adhesion molecules (CAMs)Tight junctionLeukocyte transendothelial migration

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* OriGene provides validated application data and protocol, with money back guarantee.

 

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