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Home Antibody All anti-ZWILCH antibodies

Anti-ZWILCH Antibody


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SKU Description Amount Price Availability*  
TA322300 Anti-ZWILCH Rabbit Polyclonal Antibody 100ul $325 2-3 Weeks
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OriGene Data

ImmunogenSynthetic peptide corresponding to a region derived from 249-450 amino acids of human zwilch kinetochore protein
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration3.5mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1:1000-5000
Predicted MW Explanation 67kDa
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target Namezwilch kinetochore protein
Alternative NameKNTC1AP|hZwilch
Database LinkNP_060445
Entrez Gene 55055 Human
Entrez Gene 68014 Mouse
Entrez Gene 691493 Rat
FunctionThis protein is essential component of the mitotic checkpoint; which prevents cells from prematurely exiting mitosis. And it is required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. ZWILCH gene is deleted in a patient suffering from colorectal cancer with chromosomal instability.
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Predicted band size: 67 kDa. Positive control: HT-29 and hela cell lysate. Recommended dilution: 1/1000-5000. (Gel: 8%SDS-PAGE Lane1: HT-29 cell lysate Lane2: HT-29 cell lysate Lysates: 40 ug per lane Primary antibody: 1/1750 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 3 seconds)


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