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Home Antibody All anti-HLA-DRA antibodies

Anti-HLA-DRA Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA322280
  • Anti-HLA-DRA Rabbit Polyclonal Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC412738) , 20ug Explanation
100ul 325 2-3 Weeks
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WB(1)
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Also for HLA-DRA (NM_019111)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenFusion protein corresponding to a region derived from 26-216 amino acids of human major histocompatibility complex, class II, DR alpha
Clone Name IsotypeIgG
Species ReactivityHuman; Mouse; Rat Concentration1.82mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1:500-2000
Predicted MW Explanation 29kDa
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens major histocompatibility complex, class II, DR alpha (HLA-DRA)
Alternative NameHLA-DRA1; MLRW
Database LinkNP_061984
Entrez Gene 3122 Human
FunctionHLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5.
Related PathwayTransmembrane Cell adhesion molecules (CAMs)Antigen processing and presentationHematopoietic cell lineageType I diabetes mellitusAsthmaAutoimmune thyroid diseaseMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Predicted band size: 29 kDa . Positive control: Raji cell lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lysate: 40 ug Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)

 

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