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Home Antibody All anti-EDAR antibodies

Anti-EDAR Antibody

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SKU Description Amount Price Availability*  
TA321893 Anti-EDAR Rabbit Polyclonal Antibody 100ul $325 In Stock
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IHC(1)

OriGene Data

ImmunogenSynthetic peptide corresponding to a region derived from 148-161 amino acids of Human Ectodysplasin-A receptor
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.8mg/ml
Guaranteed Application *IHC Suggested DilutionsELISA: 1:500-5000, IHC: 1:10-50
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target Nameectodysplasin A receptor
Alternative NameDL|ECTD10A|ECTD10B|ED1R|ED3|ED5|EDA-A1R|EDA1R|EDA3|HRM1
Database LinkNP_071731
Entrez Gene 10913 Human
Entrez Gene 13608 Mouse
Entrez Gene 365581 Rat
FunctionThis gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A; and can activate the nuclear factor-kappaB; JNK; and caspase-independent cell death pathways. It is required for the development of hair; teeth; and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.
Related PathwayTransmembraneDruggable Genome Cytokine-cytokine receptor interaction

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IHC Image
Predicted cell location: Cytoplasm, Cell membrane . Positive control: Human lung cancer tissue. Recommended dilution: 1/10-50 The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using EDAR antibody at dilution 1/15, on the right is treated with the synthetic peptide. (Original magnification: x200)
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