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Home Antibody All anti-BRAF antibodies

Anti-BRAF Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA321645
  • Anti-BRAF Rabbit Polyclonal Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401382) , 20ug
100ul 325 2-3 Weeks
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WB(1)
IHC(1)
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Also for BRAF (NM_004333)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenSynthetic peptide corresponding to a region derived from 591-607 amino acids of Human v-raf murine sarcoma viral oncogene homolog B1
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1.4mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsELISA: 1:1000-5000, WB: 1:500-2000, IHC: 1:50-200
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens B-Raf proto-oncogene, serine/threonine kinase (BRAF)
Alternative NameB-RAF1; BRAF1; NS7; RAFB1
Database LinkNP_004324
FunctionThis gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway; which affects cell division; differentiation; and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome; a disease characterized by heart defects; mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers; including non-Hodgkin lymphoma; colorectal cancer; malignant melanoma; thyroid carcinoma; non-small cell lung carcinoma; and adenocarcinoma of lung. A pseudogene; which is located on chromosome X; has been identified for this gene.
Related Pathway
Focal Adhesion
MAPK signaling pathway
Senescence and Autophagy

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Predicted band size: 84 kDa . Positive control: HT-29 cell lysate. Recommended dilution: 1/500-2000. (Gel: 8%SDS-PAGE Lysate: 50 ug Primary antibody: 1/1000 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 5 minutes)
IHC Image
Predicted cell location: Cytoplasm. Positive control: Human liver cancer tissue. Recommended dilution: 1/50-200 The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using BRAF antibody at dilution 1/40, on the right is treated with the synthetic peptide. (Original magnification:x200)

 

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