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Home Antibody All anti-BECN1 antibodies

Anti-BECN1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA321595
  • Anti-BECN1 Rabbit Polyclonal Antibody
100ul 325 2-3 Weeks
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IHC(2)
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Also for BECN1 (NM_003766)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenSynthetic peptide corresponding to a region derived from 50-65 amino acids of Human beclin 1, autophagy related
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.6mg/ml
Guaranteed Application *IHC Suggested DilutionsELISA: 1:1000-2000, IHC: 1:10-50
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens beclin 1, autophagy related (BECN1)
Alternative NameATG6; beclin1; VPS30
Database LinkNP_003757
Entrez Gene 8678 Human
Entrez Gene 56208 Mouse
Entrez Gene 114558 Rat
FunctionBeclin-1 is a protein that in humans is encoded by the BECN1 gene. Beclin-1 is also known as autophagy-related gene (Atg) 6. Beclin-1 and its binding partner class III phosphoinositide 3-kinase (PI3K); also named Vps34; which are participates in the regulation of autophagy and has an important role in development; tumorigenesis; and neurodegeneration. Plays a central role in autophagy. Required for the abcission step in cytokinesis. May play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus. Interacts with GOPC and GRID2. Interacts with AMBRA1. Forms a complex with PIK3C3 and PIK3R4 and either UVRAG and KIAA0226/Rubicon; or with ATG14. UVRAG and ATG14 form mutually exclusive complexes through direct competition for BECN1-binding.
Related PathwayDruggable Genome Regulation of autophagy

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

IHC Image
Predicted cell location: Cell membrane, Cytoplasm . Positive control: Human brain and tonsil tissue. Recommended dilution: 1/10-50 The image on the left is immunohistochemistry of paraffin-embedded Human brain and tonsil tissue using BECN1 antibody at dilution 1/15, on the right is treated with the synthetic peptide. (Original magnification:x200)
IHC Image
Predicted cell location: Cell membrane, Cytoplasm . Positive control: Human brain and tonsil tissue. Recommended dilution: 1/10-50 The image on the left is immunohistochemistry of paraffin-embedded Human brain and tonsil tissue using BECN1 antibody at dilution 1/15, on the right is treated with the synthetic peptide. (Original magnification:x200)

 

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