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Home Antibody All anti-CCL2 antibodies

Anti-CCL2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA321546
  • Anti-CCL2 Rabbit Polyclonal Antibody
100ul 325 2-3 Weeks
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IHC(1)
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Also for CCL2 (NM_002982)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenSynthetic peptide corresponding to a region derived from 75-89 amino acids of Human C-C motif chemokine 2
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1.9mg/ml
Guaranteed Application *IHC Suggested DilutionsELISA: 1:500-5000, IHC: 1:25-50
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens chemokine (C-C motif) ligand 2 (CCL2)
Alternative NameGDCF-2; HC11; HSMCR30; MCAF; MCP-1; MCP1; SCYA2; SMC-CF
Database LinkNP_002973
FunctionThis gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates; like psoriasis; rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.
Related Pathway
Cytokine-cytokine receptor interaction

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IHC Image
Predicted cell location: Cytoplasm . Positive control: Human breast cancer tissue. Recommended dilution: 1/25-50 The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CCL2 antibody at dilution 1/50, on the right is treated with the synthetic peptide. (Original magnification: x200)

 

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