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Home Antibody All anti-MYC antibodies

Anti-MYC PHOSPHO Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA321488
  • Anti-MYC (Phospho-Thr58) Rabbit Polyclonal Antibody
100ul 325 2-3 Weeks
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WB(1)
IHC(1)
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Also for MYC (NM_002467)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenPeptide sequence around phosphorylation site of threonine 58 (L-P-T(p)-P-P) derived from Human Myc.
Clone Name IsotypeIgG
Species ReactivityHuman; Mouse; Rat Concentration1mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:500-1000, IHC: 1:50-100
Predicted MW Explanation 60kDa
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens v-myc avian myelocytomatosis viral oncogene homolog (MYC)
Alternative NamebHLHe39; c-Myc; MRTL; MYCC
Database LinkNP_002458
Entrez Gene 4609 Human
Entrez Gene 17869 Mouse
Entrez Gene 24577 Rat
FunctionParticipates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Seems to activate the transcription of growth-related genes.
Related PathwayStem cell relevant signaling - JAK/STAT signaling pathwayStem cell relevant signaling - TGFb/BMP signaling pathwayStem cell relevant signaling - Wnt Signaling pathwayStem cell - PluripotencyEmbryonic stem cellsInduced pluripotent stem cellsTranscription FactorsDruggable Genome MAPK signaling pathwayErbB signaling pathwayCell cycleWnt signaling pathwayTGF-beta signaling pathwayJak-STAT signaling pathwayMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Predicted band size: 60 kDa . Positive control: Hela cells lysate. Recommended dilution: 1/ 500-1000. (Gel: 10%SDS-PAGE Lane1: Treated with the peptide Lane2: Hela cells lysate Lysates: 30 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)
IHC Image
Predicted cell location: Nucleus. Positive control: Human breast carcinoma tissue. Recommended dilution: 1/ 50-100 The image on the left is immunohistochemistry of paraffin-embedded human breast carcinoma tissue using MYC (Phospho-Thr58) antibody at dilution 1/50, on the right is treated with the synthetic peptide. (Original magnification: x200)

 

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