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Home Antibody All anti-EPCAM antibodies

Anti-EPCAM Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA321474
  • Anti-EPCAM Rabbit Polyclonal Antibody
100ul 325 2-3 Weeks
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IHC(1)
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Also for EPCAM (NM_002354)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenSynthetic peptide corresponding to a region derived from 300-314 amino acids of Human epithelial cell adhesion molecule
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration2.1mg/ml
Guaranteed Application *IHC Suggested DilutionsELISA: 1:1000-5000, IHC: 1:50-200
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens epithelial cell adhesion molecule (EPCAM)
Alternative NameDIAR5; EGP-2; EGP314; EGP40; ESA; HNPCC8; KS1/4; KSA; M4S1; MIC18; MK-1; TACSTD1; TROP1
Database LinkNP_002345
Entrez Gene 4072 Human
Entrez Gene 17075 Mouse
Entrez Gene 171577 Rat
FunctionThis gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. EpCAM is a pan-epithelial differentiation antigen that is expressed on almost all carcinomas. Its constitutional function is being elucidated. It is intricately linked with the Cadherin-Catenin pathway and hence the fundamental WNT pathway responsible for intracellular signalling and polarity. It has been used as an immunotherapeutic target in the treatment of gastrointestinal; urological and other carcinomas. It is expressed in undifferentiated pluripotent stem cells.tufting enteropathy.
Related PathwayES Cell Differentiation/IPSTransmembrane

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

IHC Image
Predicted cell location: Cell membrane, Cytoplasm. Positive control: Human colon cancer tissue. Recommended dilution: 1/50-200 The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using EPCAM antibody at dilution 1/45, on the right is treated with the synthetic peptide. (Original magnification:x200)

 

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