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Home Antibody All anti-XRCC6 antibodies

Anti-XRCC6 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA321352
  • Anti-XRCC6 Rabbit Polyclonal Antibody
100ul 325 2-3 Weeks
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IHC(2)
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Also for XRCC6 (NM_001469)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFusion protein corresponding to a C terminal 300 amino acids of human X-ray repair complementing defective repair in Chinese hamster cells 6
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.4mg/ml
Guaranteed Application *IHC Suggested DilutionsELISA: 1:1000-5000, IHC: 1:10-50
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens X-ray repair complementing defective repair in Chinese hamster cells 6 (XRCC6), transcript variant 1
Alternative NameCTC75; CTCBF; G22P1; KU70; ML8; TLAA
Database LinkNP_001460
Entrez Gene 2547 Human
Entrez Gene 14375 Mouse
Entrez Gene 25019 Rat
FunctionThe p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair; transposition; and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
Related PathwayTranscription FactorsDruggable Genome Non-homologous end-joining

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

IHC Image
Predicted cell location: Nucleus. Positive control: Human colon and esophagus cancer tissue. Recommended dilution: 1/10-50 The image on the left is immunohistochemistry of paraffin-embedded Human colon and esophagus cancer tissue using XRCC6 antibody at dilution 1/10, on the right is treated with the fusion protein. (Original magnification: x200)
IHC Image
Predicted cell location: Nucleus. Positive control: Human colon and esophagus cancer tissue. Recommended dilution: 1/10-50 The image on the left is immunohistochemistry of paraffin-embedded Human colon and esophagus cancer tissue using XRCC6 antibody at dilution 1/10, on the right is treated with the fusion protein. (Original magnification: x200)

 

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