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Home Antibody All anti-BAK1 antibodies

Anti-BAK1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA321299
  • Anti-BAK1 rabbit polyclonal antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400476) , 20ug Explanation
100ul 325 2-3 Weeks
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WB(1)
IHC(1)

OriGene Data

ImmunogenFusion protein corresponding to a region derived from 4-187 amino acids of human BCL2-antagonist/killer 1
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1.8mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsELISA: 1:2000-5000, WB: 1:1000-5000,IHC: 1:50-200
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens BCL2-antagonist/killer 1 (BAK1)
Alternative NameBAK; BAK-LIKE; BCL2L7; CDN1
Database LinkNP_001179
Entrez Gene 578 Human
Entrez Gene 12018 Mouse
Entrez Gene 116502 Rat
FunctionThe protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.?
Related PathwayTransmembraneStem cell - PluripotencyDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Predicted band size: 23kDa. Positive control: Hela, A431, 293T and Jurkat cell lysate. Recommended dilution: 1/1000-5000. (Gel: 12%SDS-PAGE Lane1-4: Hela, A431, 293T and Jurkat cell lysate Lysates: 40 ug per lane Primary antibody: 1/900 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/8000 dilution Exposure time: 5 seconds)
IHC Image
Predicted cell location: Cytoplasm. Positive control: Human esophagus cancer tissue. Recommended dilution: 1/50-200 The image on the left is immunohistochemistry of paraffin-embedded human esophagus cancer tissue using BAK1 antibody at dilution 1/50, on the right is treated with the fusion protein. (Original magnification:x200)

 

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