OriGene Technologies, Inc.
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-F13A1 antibodies

Anti-F13A1 Antibody

div

Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA321063 Anti-F13A1 Rabbit Polyclonal Antibody 100ul $325 2-3 Weeks
LC400044 F13A1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
Add to Shopping Cart

spacer
WB(1)
IHC(1)
spacer
Also for F13A1 (NM_000129)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFusion protein corresponding to C terminal 250 amino acids of human coagulation factor XIII, A1 polypeptide
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsELISA: 1:1000-2000, WB: 1:200-1000, IHC: 1:15-50
Predicted MW Explanation 83kDa
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens coagulation factor XIII, A1 polypeptide (F13A1)
Alternative NameF13A
Database LinkNP_000120
Entrez Gene 2162 Human
Entrez Gene 74145 Mouse
Entrez Gene 60327 Rat
FunctionThis gene encodes the coagulation factor XIII A subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function; and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits; which are identical to those of plasma origin. Upon cleavage of the activation peptide by thrombin and in the presence of calcium ion; the plasma factor XIII dissociates its B subunits and yields the same active enzyme; factor XIIIa; as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules; thus stabilizing the fibrin clot.
Related PathwaySecreted ProteinDruggable Genome Complement and coagulation cascades

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Predicted band size: 83 kDa . Positive control: Human fetal muscle tissue lysate. Recommended dilution: 1/200-1000. (Gel: 8%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/250 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 30 minutes)
spacer
Predicted cell location: Secreted,Cytoplasm. Positive control: Human cervical cancer tissue . Recommended dilution: 1/15-50 The image on the left is immunohistochemistry of paraffin-embedded human cervical cancer tissue using F13A1 antibody at dilution 1/15, on the right is treated with the fusion protein. (Original magnification:x200)
spacer

 

spacer
Inc 5000 Healthcare Company
All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title