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Home Antibody All anti-TNF antibodies

Anti-TNF Antibody MAb1

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA320488
  • Mouse Anti-Human TNF alpha Purified (50 ug)
50ug 120 3-7 Days
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Also for TNF (NM_000594)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

Immunogen
Clone NameMAb1 Isotype
Species ReactivityHuman Concentration0.5-1mg/ml (lot dependent)
Guaranteed Application * Suggested DilutionsELISA
BufferAqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Purification Affinity purified
Note The MAb1 antibody reacts with human tumor necrosis factor-alpha (TNF-a), a 17 kDa cytokine produced by monocytes, macrophages, neutrophils, NK cells and CD4+ T cells. TNF-a has cytolytic activity against a range of tumor cells and is important in immune regulation. TNF-a forms dimers and trimers and also exists as a 26 kDa membrane bound form.
MAb1 has been reported for use in capture of human TNF alpha by ELISA. It can also be used for immunoblotting (WB) and for neutralizing TNF
alpha binding and biological activity.
The MAb1 antibody has been tested as the capture antibody in a sandwich ELISA for analysis of human TNF alpha in combination with the biotin
MAb11 antibody for detection and recombinant human TNF alpha as the standard. A suitable range of concentrations of this antibody for ELISA capture is 1-4 µg/mL. A standard curve consisting of doubling dilutions of the recombinant standard over the range of 1000 pg/mL - 8 pg/mL should be included in each ELISA plate.

Reference Data

Target NameHomo sapiens tumor necrosis factor (TNF)
Alternative NameDIF; TNF-alpha; TNFA; TNFSF2
Database LinkNP_000585
Entrez Gene 7124 Human
FunctionThe MAb1 antibody reacts with human tumor necrosis factor-alpha (TNF-α), a 17 kDa cytokine produced by monocytes, macrophages, neutrophils, NK cells and CD4+ T cells. TNF-α has cytolytic activity against a range of tumor cells and is important in immune regulation. TNF-α forms dimers and trimers and also exists as a 26 kDa membrane bound form.
Related PathwaySecreted ProteinTransmembraneTranscription FactorsDruggable Genome MAPK signaling pathwayCytokine-cytokine receptor interactionApoptosisTGF-beta signaling pathwayToll-like receptor signaling pathwayNOD-like receptor signaling pathwayMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

 

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