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Home Antibody All anti-SELE antibodies

Anti-SELE Antibody P2H3

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA320457
  • Mouse Anti-Human CD62E (E-Selectin) Purified (100 ug)
100ug 130 In Stock
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FC(1)
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Also for SELE (NM_000450)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

Immunogen
Clone NameP2H3 Isotype
Species ReactivityHuman Concentration0.5mg/ml
Guaranteed Application *FC Suggested DilutionsFlow, IHC, Functional Assay, IP
BufferAqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Purification Affinity purified

Reference Data

Target NameHomo sapiens selectin E (SELE)
Alternative NameCD62E; ELAM; ELAM1; ESEL; LECAM2
Database LinkNP_000441
FunctionThe P2H3 monoclonal antibody reacts with human CD62E, a 97-115 kDa member of the selectin family. CD62E, also known as E-selectin or endothelial-leukocyte adhesion molecule-1 (ELAM-1) is an adhesion molecule expressed by endothelial cells upon stimulation with cytokines including TNFα and IL-1β. Induced expression of CD62E during inflammatory conditions is thought to mediate leukocyte rolling including the initial interaction of neutrophils with endothelium.The P2H3 monoclonal antibody also inhibits cellular adhesion to cytokine-activated endothelial cells.
Related Pathway

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FC Image
Staining of TNF alpha-stimulated Human Umbilical Vein Endothelial Cells (HUVEC) with 0.5 ug of Mouse IgG1 kappa Isotype Control Purified (open histogram) or 0.5 ug of Anti-Human CD62E (E- Selectin) Purified (filled histogram) followed by F(ab')2 Anti-Mouse IgG PE . Total viable cells were used for analysis.

 

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