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Anti-SELE Antibody P2H3


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA320457 Mouse Anti-Human CD62E (E-Selectin) Purified (100 ug) 100ug $130 2 Weeks
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OriGene Data

Clone NameP2H3 Isotype
Species ReactivityHuman Concentration0.5mg/ml
Guaranteed Application *FC Suggested DilutionsFlow, IHC, Functional Assay, IP
BufferAqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Purification Affinity purified

Reference Data

Target NameHomo sapiens selectin E (SELE)
Alternative NameCD62E; ELAM; ELAM1; ESEL; LECAM2
Database LinkNP_000441
Entrez Gene 6401 Human
FunctionThe P2H3 monoclonal antibody reacts with human CD62E, a 97-115 kDa member of the selectin family. CD62E, also known as E-selectin or endothelial-leukocyte adhesion molecule-1 (ELAM-1) is an adhesion molecule expressed by endothelial cells upon stimulation with cytokines including TNFα and IL-1β. Induced expression of CD62E during inflammatory conditions is thought to mediate leukocyte rolling including the initial interaction of neutrophils with endothelium.The P2H3 monoclonal antibody also inhibits cellular adhesion to cytokine-activated endothelial cells.
Related PathwayTransmembraneDruggable Genome Cell adhesion molecules (CAMs)

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

FC Image
Staining of TNF alpha-stimulated Human Umbilical Vein Endothelial Cells (HUVEC) with 0.5 ug of Mouse IgG1 kappa Isotype Control Purified (open histogram) or 0.5 ug of Anti-Human CD62E (E- Selectin) Purified (filled histogram) followed by F(ab')2 Anti-Mouse IgG PE . Total viable cells were used for analysis.


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