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Home Antibody All anti-IL2RA antibodies

Anti-IL2RA Antibody BC96

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA320368 Mouse Anti-Human CD25 Purified (100 ug) 100ug $120 3-7 Days
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FC(1)
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Also for IL2RA (NM_000417)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

Immunogen
Clone NameBC96 Isotype
Species ReactivityHuman Concentration0.5-1mg/ml (lot dependent)
Guaranteed Application *FC Suggested DilutionsFlow
BufferAqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Purification Affinity purified

Reference Data

Target NameHomo sapiens interleukin 2 receptor, alpha (IL2RA)
Alternative NameCD25; IDDM10; IL2R; p55; TCGFR
Database LinkNP_000408
Entrez Gene 3559 Human
FunctionThe BC96 monoclonal antibody reacts with human CD25, the 55 kDa interleukin-2 receptor α chain (IL-2Rα). CD25 is expressed by early progenitors of T and B lineage as well as by activated mature T and B lymphocytes. By itself, CD25 binds IL-2 only with low affinity. However, CD25 associates with CD122 (IL-2 receptor β chain) and CD132 (common γ chain) to form the high affinity IL-2 receptor. CD25 plays a role in lymphocyte differentiating and activation/proliferation.
Related PathwayES Cell Differentiation/IPSTransmembraneDruggable Genome Cytokine-cytokine receptor interactionEndocytosisJak-STAT signaling pathwayHematopoietic cell lineage

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Staining of PHA stimulated human PBMC with Anti-Human CD25 PE. Appropriate isotype controls were used (open histogram). Total viable cells were used for analysis.
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