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Home Antibody All anti-CD40 antibodies

Anti-CD40 Antibody HM40-3

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA320279
  • Hamster Anti-Mouse/Rat CD40 Purified (100 ug)
100ug $150 3-7 Days
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FC(1)

OriGene Data

Immunogen
Clone NameHM40-3 Isotype
Species ReactivityMouse, Rat Concentration0.5-1mg/ml (lot dependent)
Guaranteed Application *FC Suggested DilutionsFlow, IHC, Functional Assay
BufferAqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Purification Affinity purified

Reference Data

Target NameMus musculus CD40 antigen (Cd40), transcript variant 1
Alternative NameAI326936; Bp50; GP39; HIGM1; IGM; IMD3; p50; T-BAM; Tnfrsf5; TRAP
Database LinkNP_035741
FunctionThe HM40-3 monoclonal antibody reacts with mouse and rat CD40, a 45-50 kDa type I transmembrane glycoprotein. CD40 is a member of the TNFR family and is expressed by mouse B lymphocytes, follicular dendritic cells, thymic epithelium, and a subset of peripheral T cells. CD40 regulates B cell development/maturation by inducing Ig isotype switching and in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with CD154 (gp39), its ligand on T cells, is important in T-B cell crosstalk and plays a role in costimulation and immune regulation.
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

FC Image
Staining of BALB/c splenocytes with 0.5 ug Armenian Hamster IgG Isotype Control Purified (open histogram) or 0.5 ug Anti-Mouse/Rat CD40 Purified (filled histogram) followed by Anti-Armenian Hamster IgG FITC . Total viable cells were used for analysis.

 

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