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Home Antibody All anti-CD3E antibodies

Anti-CD3E Antibody eBioG4.18 (G4.18)

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SKU Description Amount Price Availability*  
TA320271 Mouse Anti-Rat CD3 Purified (100 ug) 100ug $120 3-7 Days
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FC(1)

OriGene Data

Immunogen
Clone NameeBioG4.18 (G4.18) Isotype
Species ReactivityRat Concentration0.5-1mg/ml (lot dependent)
Guaranteed Application *FC Suggested DilutionsFlow, IHC, IP, WB
BufferAqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Purification Affinity purified

Reference Data

Target NameRattus norvegicus CD3 molecule, epsilon (Cd3e)
Alternative Name
Database LinkNP_001101610
Entrez Gene 315609 Rat
FunctionThe eBioG4.18 monoclonal antibody recognizes the rat CD3 protein. CD3 is a critical component of the T-cell receptor (TCR) and is a marker of the T-cell lineage. CD3 is a complex of several subunits and, upon binding of a TCR ligand, participates in transduction of signals from the TCR to the nucleus which results in a variety of cellular responses including transcription of IL-2 and clonal expansion. in vitro, immobilized G4.18 monoclonal antibody has been demonstrated to activate T cells, while soluble G4.18 inhibited allogeneic mixed-lymphocyte proliferative responses and cell-mediated cytotoxicity to allogeneic target cells. in vivo, G4.18 was demonstrated to induce long-term specific tolerance to an organ allograft.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Staining of rat splenocytes with 0.25 ug of Mouse IgG3 Isotype Control Purified (open histogram) or 0.25 ug of Anti-Rat CD3 Purified (filled histogram) followed by Anti-Mouse IgG Biotin and Streptavidin PE . Cells in the lymphocyte gate were used for analysis.
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