Home Antibody All anti-CREB3 antibodies
Also for CREB3 (NM_006368)
|Peptide with sequence C-HHDHTYSLPRET, from the internal region of the protein sequence according to NP_006359.3|
|Test: Human. Expected from seq similarity: Human
||WB: 0.3-1ug/ml, ELISA: 1:128,000
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
|Homo sapiens cAMP responsive element binding protein 3 (CREB3)|
Entrez Gene 10488 Human
|This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-response element and regulates cell proliferation. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. This protein also plays a role in leukocyte migration, tumor suppression, and endoplasmic reticulum stress-associated protein degradation. Additional transcript variants have been identified, but their biological validity has not been determined.[provided by RefSeq, Nov 2009].|
|Transcription Factors MelanogenesisHuntington's diseaseProstate cancer|
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Anti-CREB3 (0.3ug/ml) staining of HepG2 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.