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Also for CREB1 (NM_004379)
|Peptide with sequence C-DSQESVDSVTDSQK, from the internal region of the protein sequence according to NP_004370.1; NP_604391.1|
||WB: 0.1-0.3ug/ml, ELISA: 1:128,000
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide (Protein A or G Sepharose)
|Homo sapiens cAMP responsive element binding protein 1 (CREB1), transcript variant A|
|This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].|
EGFR1 Signaling Pathway
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Anti-CREB1 (0.1ug/ml) staining of Jurkat nuclear lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.