Home Antibody All anti-CASP6 antibodies
Also for CASP6 (NM_001226)
|Peptide with sequence NRKVSQRRVDFCKDP, from the internal region of the protein sequence according to NP_001217.2; NP_116787.1|
||WB: 0.5-1.5ug/ml, ELISA: 1:128,000
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide (Protein A or G Sepharose)
|Homo sapiens caspase 6, apoptosis-related cysteine peptidase (CASP6), transcript variant alpha|
|This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms. [provided by RefSeq, Jul 2008].|
MAPK signaling pathway
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Anti-CASP6 (0.5ug/ml) staining of Human Colon lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.