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Home Antibody All anti-CASP6 antibodies

Anti-CASP6 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA320213 Goat Polyclonal Caspase 6 (alpha) Antibody 100ug $325 3-7 Days
LC400490 CASP6 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for CASP6 (NM_001226)
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OriGene Data

ImmunogenPeptide with sequence NRKVSQRRVDFCKDP, from the internal region of the protein sequence according to NP_001217.2; NP_116787.1
Clone Name IsotypeIgG
Species ReactivityTest: Human. Expected from seq similarity: Human, Mouse, Rat, Dog, Pig, Cow Concentration0.5mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 0.5-1.5ug/ml, ELISA: 1:128,000
Predicted MW Explanation 33.3kDa
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Reference Data

Target NameHomo sapiens caspase 6, apoptosis-related cysteine peptidase (CASP6), transcript variant alpha
Alternative NameMCH2
Database LinkNP_001217
Entrez Gene 839 Human
Entrez Gene 12368 Mouse
Entrez Gene 83584 Rat
Entrez Gene 487899 Dog
FunctionThis gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms. [provided by RefSeq, Jul 2008].
Related PathwayProteaseStem cell - PluripotencyDruggable Genome Apoptosis

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Anti-CASP6 (0.5ug/ml) staining of Human Colon lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.


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