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Home Antibody All anti-KIT antibodies

Anti-KIT Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA320207
  • Goat Polyclonal KIT/CD117 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC420696) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
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Also for KIT (NM_001093772)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenPeptide with sequence KRDSFICSKQEDH, from the internal region of the protein sequence according to NP_000213.1; NP_001087241.1
Clone Name IsotypeIgG
Species ReactivityTest: Human. Expected from seq similarity: Human, Dog, Pig, Cow Concentration0.5mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1-3ug/ml, ELISA: 1:128,000
Predicted MW Explanation 110kDa
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
Note An additional band of unknown identity was also consistently observed at 35kDa. This band was successfully blocked by incubation with the immunizing peptide.

Reference Data

Target NameHomo sapiens v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (KIT), transcript variant 2
Alternative NameC-Kit; CD117; PBT; SCFR
Database LinkNP_001087241
Entrez Gene 3815 Human
Entrez Gene 403811 Dog
FunctionThis gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Related PathwayProtein KinaseES Cell Differentiation/IPSTransmembraneStem cell - PluripotencyAdult stem cellsEmbryonic stem cellsDruggable Genome Cytokine-cytokine receptor interactionEndocytosisHematopoietic cell lineageMelanogenesisPathways in cancerAcute myeloid leukemiaMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Anti-KIT (1ug/ml) staining of Human Hippocampus lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

 

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