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Anti-IRF2BP2 Antibody Polyclonal
Also for IRF2BP2 (NM_182972)
|IRF2BP2 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human IRF2BP2.|
||ELISA, WB: 1 ug/ml, ICC: 2.5 ug/ml
|IRF2BP2 Antibody is supplied in PBS containing 0.02% sodium azide.|
|IRF2BP2 Antibody is affinity chromatography purified via peptide column. (Protein A or G Sepharose)
|Homo sapiens interferon regulatory factor 2 binding protein 2 (IRF2BP2), transcript variant 1|
|IRF2BP2 Antibody: IRF2BP2, like the related protein IRF2BP1, is a co-repressor that interacts specifically with the C-terminal repression domain of Interferon Regulatory Factor 2 (IRF2). IRF2BP2 is a direct target gene of p53 and is involved in cell survival during the p53 stress response, able to impede the p53-mediated transactivation of p21 and Bax. IRF2BP2 is also a co-factor of VGLL4 and is required to induce the expression of vascular endothelial growth factor A (VEGF-A) in muscle. It is normally found in the nucleus of skeletal muscle and cardiac cells, but can be found in the cytoplasm during skeletal muscle differentiation.|
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Western blot analysis of IRF2BP2 in HeLa cell lysate with IRF2BP2 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide
Immunocytochemistry of IRF2BP2 in A20 cells with IRF2BP2 antibody at 2.5 ug/mL.