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Home Antibody All anti-IRF2BP2 antibodies

Anti-IRF2BP2 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA320180
  • Rabbit Polyclonal IRF2BP2 Antibody
100ug 325 3-7 Days
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WB(1)
IF(1)
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Also for IRF2BP2 (NM_182972)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenIRF2BP2 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human IRF2BP2.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 1 ug/ml, ICC: 2.5 ug/ml
BufferIRF2BP2 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification IRF2BP2 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens interferon regulatory factor 2 binding protein 2 (IRF2BP2), transcript variant 1
Alternative NameMGC72189
Database LinkNP_892017
Entrez Gene 359948 Human
Entrez Gene 270110 Mouse
FunctionIRF2BP2 Antibody: IRF2BP2, like the related protein IRF2BP1, is a co-repressor that interacts specifically with the C-terminal repression domain of Interferon Regulatory Factor 2 (IRF2). IRF2BP2 is a direct target gene of p53 and is involved in cell survival during the p53 stress response, able to impede the p53-mediated transactivation of p21 and Bax. IRF2BP2 is also a co-factor of VGLL4 and is required to induce the expression of vascular endothelial growth factor A (VEGF-A) in muscle. It is normally found in the nucleus of skeletal muscle and cardiac cells, but can be found in the cytoplasm during skeletal muscle differentiation.
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of IRF2BP2 in HeLa cell lysate with IRF2BP2 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide
IF Image
Immunocytochemistry of IRF2BP2 in A20 cells with IRF2BP2 antibody at 2.5 ug/mL.

 

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