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Anti-NSMCE2 Antibody Polyclonal
Also for NSMCE2 (NM_173685)
|MMS21 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human MMS21.|
|Human, Mouse, Rat
||ELISA, WB: 0.5 - 1 ug/ml
|MMS21 Antibody is supplied in PBS containing 0.02% sodium azide.|
|MMS21 Antibody is affinity chromatography purified via peptide column.
|Homo sapiens non-SMC element 2, MMS21 homolog (S. cerevisiae) (NSMCE2)|
|C8orf36; MMS21; NSE2; ZMIZ7|
|MMS21 Antibody: MMS21, also known as NSE2, is a SUMO ligase that in combination with the SMC5/6 complex is required for the prevention of DNA damage induced apoptosis by facilitating DNA repair in human cells. MMS21-dependent sumoylation is integral and important to the cohesion mechanism and mitotic progression; this function appears to be independent of SMC6. MMS21 mediates SUMO attachment to various proteins such as SMC6L1 and TRAX, and possibly the cohesin components RAD21 and STAG2. |
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Western blot analysis of MMS21 in 293 cell lysate with MMS21 antibody at (A) 0.5 and (B) 1 ug/mL.