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Home Antibody All anti-NSMCE2 antibodies

Anti-NSMCE2 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA320164
  • Rabbit Polyclonal MMS21 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC406558) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
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Also for NSMCE2 (NM_173685)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenMMS21 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human MMS21.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsELISA, WB: 0.5 - 1 ug/ml
BufferMMS21 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification MMS21 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens non-SMC element 2, MMS21 homolog (S. cerevisiae) (NSMCE2)
Alternative NameC8orf36; MMS21; NSE2; ZMIZ7
Database LinkNP_775956
Entrez Gene 286053 Human
Entrez Gene 68501 Mouse
Entrez Gene 299957 Rat
FunctionMMS21 Antibody: MMS21, also known as NSE2, is a SUMO ligase that in combination with the SMC5/6 complex is required for the prevention of DNA damage induced apoptosis by facilitating DNA repair in human cells. MMS21-dependent sumoylation is integral and important to the cohesion mechanism and mitotic progression; this function appears to be independent of SMC6. MMS21 mediates SUMO attachment to various proteins such as SMC6L1 and TRAX, and possibly the cohesin components RAD21 and STAG2.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of MMS21 in 293 cell lysate with MMS21 antibody at (A) 0.5 and (B) 1 ug/mL.

 

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