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Home Antibody All anti-BCL9L antibodies

Anti-BCL9L Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA320156
  • Rabbit Polyclonal Bcl9L Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC405481) , 20ug
100ug 325 3-7 Days
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WB(1)
IF(1)

OriGene Data

ImmunogenBcl9L antibody was raised against a 20 amino acid synthetic peptide near the amino terminus of human Bcl9L.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 1 ug/ml, ICC: 10 ug/ml
BufferBcl9L Antibody is supplied in PBS containing 0.02% sodium azide.
Purification Bcl9L Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens B-cell CLL/lymphoma 9-like (BCL9L)
Alternative NameBCL9-2; DLNB11
Database LinkNP_872363
FunctionBcl9L Antibody: Bcl9L, a homolog of Bcl9, was initially identified through a bioinformatics screening. It is expressed in fetal brain, adult lung, eye and prostate, in addition to several types of tumors including pancreatic and prostate cancers. Bcl9L has been shown to interact with beta-catenin, a target of the Wnt signaling pathway, and is required for enhanced beta-catenin-T-cell factor (TCF)-mediated transcription in colorectal tumor cells, possibly by translocating beta-catenin to the nucleus. Other studies have indicated that Bcl9L expression correlates with high nuclear grade cancer phenotype and the expression of ErbB2/HER-2 in breast cancers, suggesting that activity may occur in other types of cancer. Bcl9L has also been shown to be critical for Wnt-mediate regulation of stem cell traits in colon epithelium and adenocarcinomas which are associated with tumor invasion, metastasis, and resistance to therapy.
Related Pathway

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WB Image
Western blot analysis of Bcl9L in HeLa cell lysate with Bcl9L antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
IF Image
Immunocytochemistry of Bcl9L in HeLa cells with Bcl9L antibody at 10 ug/mL.

 

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