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Home Antibody All anti-HIGD2A antibodies

Anti-HIGD2A Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA320133
  • Rabbit Polyclonal HIG2 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC408465) , 20ug
100ug 325 3-7 Days
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WB(1)
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Also for HIGD2A (NM_138820)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenHIG2 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human HIG2.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsELISA, WB: 1 ug/ml
BufferHIG2 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification HIG2 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens HIG1 hypoxia inducible domain family, member 2A (HIGD2A)
Alternative NameRCF1b
Database LinkNP_620175
FunctionHIG2 Antibody: HIG1 and HIG2 (Hypoxia-inducible gene 1 and 2, respectively) are known to be induced by hypoxic conditions. HIG2 is induced by hypoxia and by glucose deprivation in cultured cells. In addition, tumor xenografts derived from human cervical cancer cells display increased expression of HIG1 and HIG2 when they are deprived of oxygen. Unlike HIG2, which is ubiquitously expressed and might be an activator and target of the canonical Wnt pathway, the function and the mechanisms underlying its regulation of HIG1 still remained unknown. The putative link between hypoxia and an oncogenic signaling pathway might play an important role in tumorigenesis.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of HIG2 in 3T3 cell lysate with HIG2 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.

 

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