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Anti-NLRP6 Antibody Polyclonal
Also for NLRP6 (NM_138329)
|NALP6 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human NALP6.|
||ELISA, WB: 1 ug/ml, IF: 20 ug/ml
|NALP6 Antibody is supplied in PBS containing 0.02% sodium azide.|
|NALP6 Antibody is affinity chromatography purified via peptide column. (Protein A or G Sepharose)
|Homo sapiens NLR family, pyrin domain containing 6 (NLRP6), transcript variant 1|
|AVR; CLR11.4; NALP6; NAVR; NAVR/AVR; PAN3; PYPAF5|
|NALP6 Antibody: NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction. NALP6, also known as PYPAF5, is highly expressed in granulocytes and T cells and co-localizes with the PYRIN-CARD protein ASC. Co-expression of NALP6 with ASC results in a synergistic activation of NF-κB and activated caspase-1-dependent cytokine processing, suggesting that NALP6 functions in immune cells to coordinate the transduction of pro-inflammatory signals.|
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Western blot analysis of NALP6 in human heart tissue lysate with NALP6 antibody at 1 ?g/ml in (A) the absence and (B) the presence of blocking peptide.
Immunofluorescence of NALP6 in human brain tissue with NALP6 antibody at 20 ug/mL.