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Anti-GCOM1 Antibody Polyclonal
Also for GCOM1 (NM_001018095)
|MYOZAP antibody was raised against a 18 amino acid synthetic peptide near the carboxy terminus of human MYOZAP.|
|Human, Mouse, Rat
||ELISA, WB: 1 - 2 ug/ml, IHC: 5 ug/ml, IF: 20 ug/ml
|MYOZAP Antibody is supplied in PBS containing 0.02% sodium azide.|
|MYOZAP Antibody is affinity chromatography purified via peptide column. (Protein A or G Sepharose)
|Homo sapiens GRINL1A combined protein (Gcom1), transcript variant 6|
|Gup1, Gup2, Gcom2, GRINL1A, FLJ30973, MGC126694, MGC138353|
|MYOZAP Antibody: MYOZAP, also known as GRINL1A, is a 54 kDa highly conserved cardiac protein. It is strongly expressed in the heart and lung and is a novel component of intercalated disc. MYOZAP interacts with myosin phosphatase-RhoA interacting protein (MRIP) and acts as an activator of Rho-dependent SRF signaling. Knockdown study in zebrafish results in cardiomyopathy with severe dysfunction. The MYOZAP gene is part of a complex transcript unit that includes the gene for glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A (GRINL1A). Transcription of this gene occurs at an upstream promoter, with two different groups of alternatively spliced variants: Gup for GRINL1A upstream transcripts and Gcom for GRINL1A combined transcripts.|
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Western blot analysis of MYOZAP in rat kidney tissue lysate with MYOZAP antibody at (A) 1 and (B) 2 ug/mL.
Immunohistochemistry of MYOZAP in human lung tissue with MYOZAP antibody at 5 ug/mL.