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Home Antibody All anti-PRICKLE1 antibodies

Anti-PRICKLE1 Antibody Polyclonal


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SKU Description Amount Price Availability*  
TA320109 Rabbit Polyclonal PRICKLE1 Antibody 100ug $325 3-7 Days
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OriGene Data

ImmunogenPRICKLE1 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human PRICKLE1.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 1 ug/ml, IF: 20 ug/ml
BufferPRICKLE1 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification PRICKLE1 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens prickle homolog 1 (Drosophila) (PRICKLE1), transcript variant 1
Alternative NameEPM1B; RILP
Database LinkNP_694571
Entrez Gene 144165 Human
Entrez Gene 106042 Mouse
Entrez Gene 315259 Rat
FunctionPRICKLE1 Antibody: PRICKLE1, also known as RILP or EPM1B, is a Disheveled-associated protein that serves as a nuclear translocation receptor for REST/NRSF and REST4 (1, 2). It contains three N-terminal LIM domains and three C-terminal nuclear localization signals. It localizes to the cytoplasm, as well as to the nuclear membrane and expressed at higher levels in placenta. PRICKLE1 is a negative regulator of the Wnt / beta-catenin signaling pathway and is a putative tumor suppressor in human HCCs. Defects in the gene encoding PRICKLE1 are associated with autosomal recessive progressive myoclonic epilepsy.
Related PathwayDruggable Genome Wnt signaling pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of PRICKLE1 in human bladder tissue lysate with PRICKLE1 antibody at 1 ug/mL.
Immunofluorescence of PRICKLE1 in human bladder cells with PRICKLE1 antibody at 20 ug/mL.


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