Home Antibody All anti-TMEM88 antibodies
Anti-TMEM88 Antibody Polyclonal
Also for TMEM88 (NM_203411)
|TMEM88 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human TMEM88.|
|Human, Mouse, Rat
|WB, IHC, IF
||WB: 1 ug/ml, IHC: 2.5 ug/ml, IF: 20 ug/ml
|TMEM88 Antibody is supplied in PBS containing 0.02% sodium azide.|
|TMEM88 Antibody is affinity chromatography purified via peptide column.
|Homo sapiens transmembrane protein 88 (TMEM88)|
Entrez Gene 92162 Human
Entrez Gene 67020 Mouse
Entrez Gene 497936 Rat
|TMEM88 Antibody: Transmembrane protein 88 (TMEM88) is a two-transmembrane-type protein whose C-terminal tail has been shown to bind the PDZ domain of Dishevelled (Dvl), one of the key components in Wnt signaling pathways. TMEM88 attentuated the Wnt/beta-catenin signaling induced by Wnt-1 ligand in a dose-dependent manner and knockdown of TMEM88 by RNAi increased Wnt activity, suggesting that TMEM88 plays a role in regulating Wnt signaling in a context-dependent manner. |
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Western blot analysis of TMEM88 in human brain tissue lysate with TMEM88 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
Immunohistochemistry of TMEM88 in mouse brain tissue with TMEM88 antibody at 2.5 ug/mL.
Immunofluorescence of TMEM88 in mouse brain tissue with TMEM88 antibody at 20 ug/mL.